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DBCO-PEG4-Desthiobiotin，Desthiobiotin-PEG4-DBCO
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英文：DBCO-PEG4-Desthiobiotin，Desthiobiotin-PEG4-DBCO
CAS：2032788-37-5
- 产品描述
- 参数
- 价格
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- 商品名称: DBCO-PEG4-Desthiobiotin，Desthiobiotin-PEG4-DBCO
- 商品编号: 1139575038181789696
- CAS号: 2032788-37-5
- 产品货号: Y-PE-3039
中文：脱硫生物素-四聚乙二醇-二苯并环辛炔<br>英文：DBCO-PEG4-Desthiobiotin，Desthiobiotin-PEG4-DBCO<br>CAS：2032788-37-5
DBCO-PEG4-Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kdﾊ= 1011ﾊvs. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin. DBCO is commonly used for copper-free Click Chemistry reactions.
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产品参数1
- Catalog #: Y-PE-3039
- Name: DBCO-PEG4-Desthiobiotin
- CAS: 2032788-37-5
- Formula: C39H53N5O8
- MW: 719.9
- Purity: 95%
- Availability: In Stock
- Ships within: 24 hours
- Storage condition: -20℃
- Shipping: Ambient temperature
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